Letter check · in discovery
Do your letters to doctors still reflect the current prescribing information?
When a doctor asks your company about a medicine, your medical information team often answers with a prepared letter. Many of these letters quote the prescribing information. We are designing a check with medical information teams that would compare each letter with the current version and flag what no longer reflects it.The prescribing information, which people in pharma call the label, is the official document a regulator approves for each medicine: the FDA in the US, the European Commission or a national agency in Europe, the MHRA in the UK.
In discovery, so nothing here is a finished product yet. Today, a Change Check already lists the letters you share that quote a changed part.
Letter to doctors
Varigel: the dose for patients with kidney problems
Prescribing information (the label)
Varigel, updated 4 September
For patients with moderate kidney problems, the dose is up to 20 mg once a day.
DoseChanged on 4 September
Says the old doseThe current version says start at 10 mg and take no more than 15 mg once a day.
There is little information on use in severe kidney disease.
Who should not take itChanged on 4 September
Misses the new warningThe current version says people with severe kidney disease should not take it.
More of the medicine stays in the body as the kidneys work less well.
How the body handles itMatchesMatches the current version.
Source 1: Varigel prescribing information, previous version.
SourcesCites the old versionA newer version was approved on 4 September.
What it would check
Each letter, compared with the prescribing information it quotes.
Prepared letters quote the prescribing information and published studies. Letters should reflect the current information, but when it changes, they fall behind until someone re-reads them.
What the letter quotes
Each statement that restates the prescribing information, compared with the current version, so a changed dose, a new group of patients or a new warning is caught.
The parts each letter relies on
Each paragraph tied to the parts of the prescribing information it quotes, so when a part changes, the letters that rely on it can be listed in the same week.
The sources a letter cites
Sources checked the way Juncture’s Source check works: there is a source, it supports the statement, the numbers match and it is the current version.
Who it is for
For the teams who keep letters to doctors up to date.
Medical information
You write and update the prepared letters, which many teams call standard responses. Know which letters quote a part that changed, and what in each one no longer reflects it.
Medical reviewers
You approve letters and their updates. Start each re-review from the statements that differ from the current prescribing information, with the part they quote attached.
Regulatory and labeling
You own the prescribing information. See which letters rely on the parts you are changing, next to the key messages and materials that rely on them.
How we would work with you
Four steps with your medical information team.
- 1
Talk through your letters
How many prepared letters you keep, where they are stored, how they are approved and how often they are reviewed.
- 2
Pick one medicine
A small set of approved letters for one medicine, with the current prescribing information for its country.
- 3
See what we find
The Juncture team ties each letter to the parts of the prescribing information it quotes and walks you through every statement that no longer reflects it.
- 4
Decide together
What the check should cover, how the findings should reach your team, and whether it is worth building for you.
What it would never do
- Send, approve or rewrite a letter. Your medical information and review teams decide.
- Answer a doctor’s question itself.
- Touch enquiry records, the details of who asked, or patient data.
- Train any AI model on your material.
Questions
Questions about the Letter check.
- Is the Letter check available today?
- It is in discovery. We are designing it with medical information teams before anything is built as a product. Today, a Change Check already includes the prepared letters you share for the medicine and lists the ones that quote a changed part of the prescribing information.
- What would it check?
- Prepared letters against the current prescribing information: the text a letter quotes, the parts of the prescribing information each paragraph relies on, and the sources the letter cites, including whether it cites the current version.
- Does it touch enquiry records or patient data?
- No. It works on approved letter templates and the prescribing information only. Juncture handles no patient data and never sees the individual questions doctors or patients send in.
- How do we take part?
- Book a walkthrough. We start with how your letters are written, stored and approved, then look at a small set of letters for one medicine with you and decide together what a useful check would cover.
Help shape it
Bring a few letters. See which ones still say the old thing.
Start with a sample check on one of your medicines from public information. Or book a walkthrough to talk through how your letters are kept, and look at a small set for one medicine with us.