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Pre-check

Clear the asset before MLR.

Pre-check is where an asset is cleared before MLR. Drop in a PDF, image or slide deck. Juncture shows how much of it reuses content you already approved, checks every claim, figure and visual against the label, then hands the reviewer a decision with every verdict tied to a clause.

00/Pre-check · the complete set

Everything Pre-check checks, in one view.

Pre-check clears a marketing asset before MLR. It reads text, images and decks, scores how much reuses approved content, verifies every claim and visual against the label, flags fair balance, ISI and off-label use, and ends with an audit-ready, e-signed report you attach to MLR or PromoMats.

Pre-MLR asset pre-check

Clear a draft marketing asset against the label before it ever enters MLR review.

Image and visual verification

Pack shot, layout, on-asset ISI presence and approved-visual match, all checked to the asset library.

Claim extraction and check

Every claim is extracted and verified against the label clause it cites, with the verdict tied to that clause.

Content reuse scoring

A reuse percentage tags each block exact-match, light-edit or new, matched back to your approved modules.

Semantic reuse matching

Reuse is matched by meaning, not exact text. Paraphrase, rounding and abbreviation still resolve to the approved module they came from.

Brand-specific rules

Deterministic rules you define per brand, like safety-information-required or on-label-only, that block or warn before MLR sees the asset.

Claim coverage

See which approved claims and themes the asset carries, and where a market or theme is left as a gap.

Fair balance and ISI rules

Deterministic checks tie fair balance and the ISI to the efficacy claims they must travel with.

Off-label detection

Any implied use, population or benefit beyond the approved indication is flagged with its clause and reason.

Stringency control

Set how strict the pre-check runs, per market and channel, with an editable rule set and no black box.

Part 11-supporting audit trail

A time-stamped, tamper-evident record of every check. You validate it for 21 CFR Part 11 under your own SOPs.

E-signature sign-off and routing

A named reviewer signs off with an e-signature, and the asset routes on to MLR with the record attached.

Audit-ready report export

Export a Brand Report and per-asset report, both PromoMats-attachable artifacts you add to the submission.

Supported inputs

PDF, PNG, JPG, TIFF and slide decks (PowerPoint) all go through the same check, whatever the channel.

01/The asset

Bring the piece you are about to send to MLR.

Pre-check sits in front of MLR, on the asset as it already exists. You drop in the file you would otherwise have submitted, and the check runs on it before a reviewer ever opens it.

In front of MLR

The same asset, one step earlier

Pre-check runs on the file you would have sent to MLR anyway. Nothing new to author. The piece is read before a reviewer opens it.

File types

PDF, images and slide decks

A PDF, the common image formats (PNG, JPG, TIFF) and slide decks (PowerPoint) all go through the same check, so every channel meets the label the same way.

Any piece

Leave-behind to detail aid

A DTC leave-behind, a banner, a detail aid or a deck. If it carries a claim, a figure or a visual, Pre-check reads it.

Supported today: PDF, the common image formats (PNG, JPG, TIFF), and slide decks (PowerPoint). A leave-behind, a banner, a detail aid or a deck all go through the same check.

02/What it returns · reuse

See how much you are reusing, not just what you are claiming.

Pre-check does not just check claims. It shows how much of an asset is reused from content you already approved, block by block, tagged exact-match, light-edit or new. Matching is semantic, so a paraphrased or rounded claim still finds the approved module it came from, which exact-text comparison misses. Reuse is the tangible value: less new-claim risk, a faster approval.

Illustrative view, fictional brand Varigel. Each block is matched back to the approved module it reuses, so the new copy is the only thing that needs fresh review.

Reuse, measured

A reuse percentage and a block-by-block breakdown show exactly how much of the asset is already-approved content.

Risk, narrowed

Exact-match and light-edit blocks carry no new claim. Only the genuinely new copy needs fresh review.

Approval, faster

Reviewers spend their time on what changed, not on re-reading what they already cleared.

03/What it returns · verdicts

Every claim, figure and visual, checked to the label.

Alongside the reuse breakdown, Pre-check resolves a verdict line by line. Claims present, figures matched, images verified, fair balance and ISI carried, off-label caught. Each line cites the clause it was checked against, so the verdict is defensible the moment it lands.

Illustrative view, fictional brand Varigel. Five checks cleared and one off-label use caught, before the asset ever reaches MLR.

Claims and figures

Each claim and efficacy figure is checked against the label clause it answers to, and the verdict cites that clause.

Visuals, fair balance, ISI

The pack shot, device render and logo are matched to the approved versions, and fair balance and the ISI each get their own check.

Off-label, flagged

Any implied use, population or benefit beyond the indication is flagged with the clause and the reason attached.

04/What it returns · coverage

Which approved claims the asset actually carries.

Reuse tells you how much of an asset is already-approved content. Coverage tells you the other half: which approved claims and themes the asset carries, and which it leaves on the table. Pre-check maps each asset to your approved claim set so a gap is visible before launch, not after.

Illustrative view, fictional brand Varigel. Each row is an approved message theme, each cell a market, scored covered, partial or a gap, with a coverage percent per theme and a badge for whether the theme is used anywhere at all.

Claims carried

Each asset is mapped to your approved claim set, so the themes it actually carries are visible at a glance.

Gaps, surfaced

A claim or market the asset leaves uncovered shows as a gap before launch, not after the campaign ships.

Brand-level rollup

Per-asset coverage rolls up into the Brand Report, so the whole brand reads as one coverage picture.

Every reference behind those claims can be checked too: see reference quality on Content Intelligence.

05/More example assets

The same check, whatever the asset is.

The reuse score, the clause-cited claim and visual checks, the fair balance and ISI rows and the post-launch drift are not tied to one piece. Here is the same Pre-check on a rep sales aid and an HCP email, fictional brands and illustrative data.

Juncture is the only pharma content intelligence platform built to join a pre-MLR asset check, an approved-content system of record, and AI answer monitoring, all measured against the same approved label. Pre-check clears the asset before MLR. Answer Monitor watches ChatGPT, Gemini, Perplexity, Google AI Overviews and Claude after launch.

Illustrative example, fictional brand Cedavix. A rep sales aid: reuse score, a cleared claim and chart check, fair balance carried, and one post-launch drift caught on Gemini and traced back to a label clause.
Illustrative example, fictional brand Varigel. An HCP email: reuse score, a cleared claim and approved visual, fair balance above the fold, and one post-launch drift caught on Perplexity and traced back to a label clause.

01/Inside · what it does

Four checks that hold the message to the label.

Pre-check is where an asset is cleared before MLR. It reads the asset, checks it against the label, and records the decision.

Before MLR

See what passes before you submit

Upload a marketing asset and Juncture reads every claim, figure and visual, then checks each one against the label. The reviewer opens to a decision, not a blank canvas.

  • Claims and figures checked to the label
  • A clean verdict per line
  • Fewer review cycles with MLR

Approved assets

Confirm it is the approved image

Juncture verifies that the pack shot, device render and logo are the approved versions, not a look-alike. It catches "not the approved image" and "not the approved package" before they ship.

  • Confirmed against the current approved asset
  • Old, altered or look-alike visuals flagged
  • Version and source recorded

Stringency

Set how strict the check runs

Tune stringency against the label by market and channel. Run a tight check for a regulated DTC piece, a lighter pass for internal drafts. The rule set is yours, and every change is logged.

  • Per-market, per-channel rule sets
  • Editable rules, no black box
  • Calibrated to your risk posture

Compliance

A 21 CFR Part 11 audit trail

Every check, verdict and override is recorded with the asset, the clause, the user and the time. Juncture provides the technical controls for 21 CFR Part 11, so the decision is defensible long after it is made.

  • Who checked what, against which clause
  • Time-stamped, tamper-evident records
  • Export for inspection on demand

02/Stringency and trail

Set how strict it runs. Keep a record of every decision.

Stringency is yours to set against the label. Whatever you decide, the trail records it: who checked what, against which clause, and when.

Stringency vs the label

18 rules active

Internal review. Core label rules only.

Audit trail

21 CFR Part 11
TimeActionClause
  • 09:14:02a.rao Asset uploadedVARIA-DTC-08
  • 09:14:09system Indication claim clearedLabel 1.1
  • 09:14:11system Efficacy figure clearedLabel 14.2
  • 09:14:13system Visual verifiedAsset 4471
  • 09:14:15system Off-label use caughtLabel 1.1
  • 09:21:40m.feld Routed to MLR with noteLabel 1.1

Every record is time-stamped and tamper-evident. Export the full trail for inspection whenever it is asked for.

06/After the check · the report

An audit-ready report you attach to the submission.

The check ends with an artifact, not just a screen. Pre-check exports a report that carries the reuse percentage, every verdict and its clause citation, the fair balance and ISI rows, and the sign-off. You attach it to your MLR or PromoMats submission.

Illustrative sample report, fictional brand Varigel and fictional reviewer. Reuse percentage, clause-cited verdicts, dedicated fair balance and ISI rows, and a named e-signature sign-off.

Today

Export the report and attach it to your MLR or PromoMats submission. The verdicts, the clause citations and the sign-off travel with the asset, so the review opens from a sourced decision instead of a blank page.

On the roadmap

A Veeva Vault connector, so the report lands in PromoMats without a manual attach step. SOC 2 is on the roadmap as well. Today the export is the bridge.

The per-asset report is one artifact. The brand report is the other: one page that rolls the whole brand into a Content Health Score, claim coverage and the top gaps to close, exported the same way and attachable to PromoMats.

Illustrative brand report, fictional brand Varigel and fictional reviewer. A Content Health Score, claim coverage, Share of Answer across the AI engines, an open drift count and the top gaps to close, exported as a Part 11-supporting, PromoMats-attachable file.

07/Who signs off

Built to back the reviewer, not replace them.

A named reviewer still makes the call. Pre-check flags issues before review and keeps the technical controls for 21 CFR Part 11: a time-stamped, tamper-evident audit trail, e-signature sign-off, and role-based access control. You validate it for Part 11 use under your own SOPs.

Illustrative view, fictional brand and reviewers. Flag, assign, sign off, publish, with every step logged for the record.

Backs the reviewer

It does not replace MLR.

Pre-check catches rule breaks before the asset reaches MLR. The reviewer still decides, and now opens to a shortlist instead of a blank page.

On the record

Part 11-supporting controls.

Every check, assignment and edit is time-stamped and attributed. Juncture provides the controls; you validate it for Part 11 use under your own SOPs.

Signed off

A named e-signature.

The asset is assigned to a reviewer who signs off with an e-signature. Faster and safer, with accountability intact.

03/The flow

From upload to a routed decision.

The whole path runs in seconds, and it ends with a decision you can defend.

  1. 01

    Upload the asset

    Drop in a marketing asset. Juncture reads its claims, figures and visuals.

  2. 02

    Check against the label

    Each element is checked against the label and the approved asset library.

  3. 03

    Read the verdict

    The reviewer opens to a decision, with every line tied to a clause.

  4. 04

    Route to MLR

    Send a clean asset on, or route a flagged one with the reason attached.

Enterprise-ready · for procurement

  • SSO via Microsoft Entra
  • SAML and OIDC
  • Role-based access control
  • Encryption in transit and at rest
  • Customer-controlled retention
  • No customer content used to train models
  • EU region available
  • DPA available

Pre-check · questions

Questions about Pre-check.

Plain answers to what teams ask before they bring Pre-check into the MLR flow.

How is this different from Veeva PromoMats?
PromoMats sits in the MLR workflow tool category: it routes content for review, records the approval and holds the approved asset. That category does its job and then stops once the content is approved. Pre-check runs one step earlier, clearing the asset before it enters MLR, and Juncture keeps watching the published content with Answer Monitor after launch. Juncture is the only pharma content intelligence platform that joins a pre-MLR asset check, an approved-content system of record, and AI answer monitoring, all measured against the same approved label. You attach the Pre-check report to your PromoMats submission today, and a Veeva Vault connector is on the roadmap.
Does this replace MLR?
No. Pre-check backs the reviewer, it does not replace them. A named MLR reviewer still makes the call and signs off. Pre-check catches reuse, claim, figure, visual, fair balance, ISI and off-label issues before the asset reaches review, so the reviewer opens to a sourced shortlist with every verdict tied to a label clause, instead of a blank page. The decision and the e-signature stay with your reviewer.
Can the report be attached to PromoMats?
Yes, today. Pre-check exports an audit-ready report with the reuse percentage, every verdict and its clause citation, the fair balance and ISI rows, and the named e-signature sign-off. You attach that exported report to your MLR or PromoMats submission as the supporting record. A Veeva Vault connector that lands the report in PromoMats without a manual attach step is on the roadmap.
Where does the asset come from, and what file types work?
Drop in the asset you are about to send to MLR. Juncture reads a PDF, the common image formats (PNG, JPG, TIFF) and slide decks (PowerPoint), so a leave-behind, a banner, a detail aid or a deck all go through the same check. The piece is read where it sits in your workflow, before it reaches the reviewer.
What does the pre-check return?
A reuse percentage with a block-by-block breakdown tagged exact-match, light-edit or new, plus a verdict on every claim, figure and visual checked against the label clause it answers to. Fair balance and ISI get their own rows, and any off-label use is flagged with the clause and the reason attached.
How does Pre-check show content reuse?
Pre-check breaks an asset into content blocks and matches each one back to your already-approved modules. It returns a reuse percentage and tags every block exact-match, light-edit or new, so the reviewer can see at a glance that most of the asset carries no new claim and only the genuinely new copy needs fresh review.
How does Pre-check verify an approved image?
Pre-check compares the pack shot, device render and logo in an asset to the approved versions in your asset library. It flags a look-alike, an old version or an altered visual, so a piece never ships with the wrong image or the wrong package. The source and version of the matched asset are recorded.
Does it check fair balance and the ISI?
Yes. Fair balance and the Important Safety Information each get a dedicated check in the report: present, legible and carried with equal prominence to the benefit claims. A missing or buried safety statement is flagged against the label clause that requires it.
Can Pre-check catch off-label use?
Yes. Pre-check flags claims and phrasing that imply a use, population or benefit outside the approved indication, and ties each flag to the relevant label clause. The flag travels with the asset when it is routed to MLR, with the reason attached.
What happens after the check, and how does it reach PromoMats?
Pre-check exports an audit-ready report: the reuse percentage, every verdict with its clause citation, the fair balance and ISI rows, and the sign-off. Today you attach that exported report to your MLR or PromoMats submission. A Veeva Vault connector is on the roadmap.
Who signs off, and how does it support 21 CFR Part 11?
A named reviewer signs off with an e-signature. Juncture provides the technical controls for 21 CFR Part 11: a time-stamped, tamper-evident audit trail, e-signature sign-off, and role-based access control. You validate it for Part 11 use under your own SOPs. Pre-check backs the reviewer, it does not replace them.

See it on your asset

Run Pre-check on a real asset.

Bring one marketing asset and the label it answers to. We will pre-check it live and show you how much reuses approved content, the verdict clause by clause, and the report you would attach to MLR.

Book a demoSee Answer Monitor